Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment Cot Statement on Physiologically Based Pharmacokinetic Modelling
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چکیده
1. In February 2003 the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) hosted a workshop on physiologically based pharmacokinetic (PBPK) modelling. The workshop comprised several presentations; these considered the use of PBPK models in risk assessment, requirements for PBPK models and parameters for incorporation of PBPK methods into risk assessment. The presentations were followed by a general discussion which focussed on the strengths and weaknesses of PBPK modelling, whether PBPK models could be integrated into COT risk assessments and how this could be achieved.
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تاریخ انتشار 2004